منابع مشابه
Decreased Response to Acetylcholine during Aging of Aplysia Neuron R15
How aging affects the communication between neurons is poorly understood. To address this question, we have studied the electrophysiological properties of identified neuron R15 of the marine mollusk Aplysia californica. R15 is a bursting neuron in the abdominal ganglia of the central nervous system and is implicated in reproduction, water balance, and heart function. Exposure to acetylcholine (...
متن کاملSynaptic actions of identified peptidergic neuron R15 in Aplysia. I. Activation of respiratory pumping.
The purpose of the study described in this and the following two companion papers was to determine the synaptic actions of neuron R15, an endogenously bursting neurosecretory cell in Aplysia, as a step toward determining its physiological function. The results described in this paper demonstrate that activity in R15 increases the frequency of bursting in the R25/L25 network that triggers respir...
متن کاملModeling interactions between electrical activity and second-messenger cascades in Aplysia neuron R15.
The biophysical properties of neuron R15 in Aplysia endow it with the ability to express multiple modes of oscillatory electrical activity, such as beating and bursting. Previous modeling studies examined the ways in which membrane conductances contribute to the electrical activity of R15 and the ways in which extrinsic modulatory inputs alter the membrane conductances by biochemical cascades a...
متن کاملA cyclic GMP analog decreases the currents underlying bursting activity in the Aplysia neuron R15.
Bath application of 8-parachlorophenylthio-cyclic GMP (8-pcpt-cGMP) has been shown to increase the number of action potentials per burst in the Aplysia neuron R15. Here we report that 8-pcpt-cGMP can eventually inhibit R15's bursting activity and cause the cell to exhibit slow tonic spiking activity. This action is preceded by decreases in spike frequency and in the amplitude of the interburst ...
متن کاملPatterns of proteins synthesized in the R15 neuron of Aplysia. Temporal studies and evidence for processing
The time-course of changes in the pattern of newly synthesized proteins in the R15 neuron of the parietovisceral ganglion of Aplysia californica has been studied at 14 degrees C. 5% polyacrylamide gels containing sodium dodecyl sulfate (SDS) have been used to separate newly synthesized (leucine-labeled) proteins from the neuron. We have demonstrated that the pattern of newly synthesized protein...
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ژورنال
عنوان ژورنال: Scholarpedia
سال: 2011
ISSN: 1941-6016
DOI: 10.4249/scholarpedia.4181